Satiety The Key To Weight LossIntroduction:

The research is quite clear that safe and effective weight loss is not about will power, deprivation, or counting calories. Ultimately, weight loss success is most often attributed to strategies and tools that impact appetite and portion control. In particular, the ability to experience satiety is big factor for success.

Satiety is defined as the state of being full or gratified to the point of satisfaction. Research has shown that humans eat to achieve satiety and those who are overweight have a disordered appetite regulation typified by an increased frequency of food cravings, and a resistance to satiety after eating adequate amounts of food.

New research on promoting satiety with the revolutionary dietary fiber matrix PGX®, once again, establishes it as an extremely effective weight loss tool. In fact, I believe that PGX® is the Holy Grail of weight loss based upon the impressive results it has shown in detailed clinical and experimental studies, including a new study published in the medical journal Physiology & Behaviour on its ability to promote satiety.

Background Data:

PolyGlycoPlex (PGX®) is the most viscous and soluble fiber known. It is produced in a patented process that allows three natural fibers to coalesce and form a matrix that has a higher level of viscosity, gel-forming properties, and has more expansion with water, than any other fiber. In essence, it is a “super” fiber with all of the beneficial effects of fiber, but are magnified and more easily attained with PGX®.

Clinical studies published in major medical journals and presented at the world’s major medical conferences have shown PGX® to exert the following benefits:

  • Increases the level of compounds that block the appetite and promote satiety.
  • Decreases the level of compounds that stimulate overeating.
  • When taken prior to a meal can increase the feeling in fullness, very hungry to very full.
  • It reduces the glycemic index of any food, beverage, or meal by as much as 70%.
  • Increases insulin sensitivity and promotes improved blood sugar control.
  • Helps stabilize blood sugar levels to reduce food cravings.

New Data:

Previous studies have shown that PGX® granules and PGX®-based meal replacement formulas are very effective at promoting satiety leading to a reduction in calories consumed. To test the effects of PGX® capsules, 14 healthy adult women participated in a controlled study. The effects on the level of satiety for 2 hours after eating a standardized evening meal when the PGX® capsules were given was compared to the same meal without PGX®. Also, on the following morning, after an overnight fast, the four hour satiety response to a standardized breakfast with no PGX® supplementation was assessed. This second assessment was designed to measure the “second meal effect” of PGX. The second-meal effect measures the effect the first meal has on the blood sugar level after eating the second meal.

Results showed a statistically significant higher satiety response to the standard dinner for the PGX-supplemented dinner compared with the control dinner (p = 0.001) was found. In addition, the fullness scores of the breakfast following the PGX®-supplemented dinner at 15, 30, 90, 120, 150, 180, 210 and 240 minutes were significantly higher than those for the breakfast following the control dinner. These results show that PGX® supplementation at dinner increased the satiety effects of both the dinner itself and the subsequent un-supplemented breakfast. Hence, PGX® demonstrated a significant second meal effect indicating PGX® has the ability to induce extended satiety far beyond the just the meal it is taken before.


First, if you did not catch it previously, watch my webinar on Preventing Holiday Weight Gain. PGX® can be very helpful in this goal.

In my opinion, PGX® is the most important natural product in North America today because of its ability to address the core underlying reasons why weight loss and blood sugar control are often so difficult to achieve. Yes, I played a role in the development of PGX®, so some may say that I am severely biased. My response is that I am biased, but it is not because of any financial benefit. My bias is a reflection of the powerful effect that I have seen this safe and effective natural product have on changing people’s lives. I want everyone who has struggled with weight loss to give PGX a try. My hope is that it will change your life, as it has changed the lives of so many others. It works!!

For more information on PGX and practical guidelines to insure weight loss success, please go to


Yong MK, Solah VA, Johnson SK, et al. Effects of a viscous-fibre supplemented evening meal and the following un- supplemented breakfast on post-prandial satiety responses in healthy women, Physiology & Behavior 2015:doi 10.1016/j.physbeh.2015.11.006 [Epub ahead of print]

Dr. Michael Murray

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