Theracurmin Super – The Most Advanced Form of Curcumin

Theracurmin Super – The Most Advanced Form of Curcumin

 

Curcumin, the yellow pigment and key compound of turmeric ( Curcuma longa ) has become one of the most popular dietary supplements EVER. However, regular curcumin powder is probably   a waste of money as detailed absorption studies have conclusively shown that regular curcumin as well as curcumin in combination with piperine from black pepper is poorly absorbed. ^1-4

 

Without absorption, curcumin will not produce the full health benefits people are looking for. To see the results with curcumin, it is necessary to use a form that has shown both enhanced absorption and proven clinical efficacy. Of these forms, Theracurmin has the most impressive results in double-blind, placebo-controlled studies. Beneficial effects noted include the ability to reduce tissue damage caused by inflammation, improve liver function, increase the ability of the heart to function more efficiently, promote vascular elasticity, enhance and protect brain function, and, lastly, improve quality-of-life scores. ^5-10

 

In these human clinical trials, Theracurmin has shown superior health benefits compared to all other forms of curcumin – until now….

 

Theracurmin vs. Theracurmin Super

The production of Theracurmin utilized advanced manufacturing techniques to reduce the particle size of curcumin and then solubilize it in a colloidal suspension within a vegetable gum. This new form, named Theracurmin Super, utilizes new, ground-breaking technology.

 

The reason curcumin is poorly absorbed is because its physical state is in the form of a poorly soluble crystal. With Theracurmin, the size of the crystal is reduced, so it becomes a little more soluble, but it is still poorly soluble.

 

In contrast, Theracurmin Super is extremely soluble. To produce Theracurmin Super, regular curcumin is processed into an amorphous, non-crystalline form that is significantly more water soluble and easier to absorb.

 

Detailed human studies show the absorption curcumin from Theracurmin Super is more than 3 times better absorbed than the curcumin provided in regular Theracurmin® and more than 85 times better absorbed than regular crystalline curcumin. ^11,12

 

The superiority of Theracurmin Super to Theracurmin has been shown in a linear progression of science. It started with pre-clinical data, moved on to absorption studies in humans, and finally in controlled human clinical trials. ^11-15

 

Clinical Studies with Theracurmin Super

Four human double-blind, placebo-controlled clinical studies have already been completed with Theracurmin Super and more are in process. In the first study, Theracurmin Super at a dosage of 150 mg daily for 12 weeks produced significant benefits in improving upper respiratory tract symptoms associated with the common cold compared to regular Theracurmin at the same dosage or a placebo. ¹²

 

The subjects taking Theracurmin Super showed twice as high total curcumin concentration in blood than those on regular Theracurmin. Though regular Theracurmin® showed some benefits, the higher absorption of curcumin from Theracurmin Super translated to significantly decreased sneezing, nasal discharge, nasal obstruction, and coughing with Theracurmin Super supplementation compared to regular Theracurmin. ¹²

 

In another study, improvements in both mood status and vascular function were noted with Theracurmin Super. Ninety healthy adults were randomized to take either Theracurmin Super at a daily dosage of 150 mg or a placebo for 12 weeks. Improvements with Theracurmin Super® related to mood were seen with the group reduced feelings of anger, hostility, and depression. ¹³

 

Results also showed that Theracurmin Super influenced vascular function by reducing sympathetic nervous system activity while promoting parasympathetic nervous system activity in people over 40 years of age, which may also help positively influence mood as well. Theracurmin Super also helped improve vascular function and reduce vascular age.

 

In the most recent study, 71 healthy adults took either Theracurmin Super (curcumin, 120 mg/day) or Placebo (curcumin, 0 mg/day) for 8 weeks. Results showed Theracurmin Super effectively reduced oxidative stress before and after exercise, verifying curcumin's important application in reducing oxidative stress. Significant improvements in total oxidant status (TOS) and the oxidative stress index (OSI) were demonstrated. ¹⁴

 

Lastly, in a double-blind, placebo-controlled, human safety study, Theracurmin Super® was shown to be safe at dosages of 150 mg a day for 12 weeks and 750 mg per day for four weeks with no side effects or any indication of an adverse effect. ¹⁵

 

Clearly, Theracurmin Super® represents a major advancement in providing the health benefits of curcumin.

 

Theracurmin Super from Dr. Murray Natural Products

One of my goals in designing my product line was to use ingredients that are the “gold standards.” ThymoQuin® was the first dietary supplement introduced in the Dr. Murray Natural Products line is without question the gold standard in black seed oil supplements. Theracurmin Super can also be viewed as a gold standard for curcumin.

I’m deeply committed to helping people achieve real results through natural medicine—it’s at the heart of my life’s mission. I believe Theracurmin Super offers the most effective form of curcumin available, giving individuals the best opportunity to experience its full benefits. That said, there are other excellent clinically effective forms available. The bottom line is to make sure you are using one of these forms!

 

References:

1. Fança-Berthon P, Tenon M, Bouter-Banon SL, et al. Pharmacokinetics of a Single Dose of Turmeric Curcuminoids Depends on Formulation: Results of a Human Crossover Study. J Nutr. 2021 Jul 1;151(7):1802-1816.

2. Flory S, Sus N, Haas K, Jehle S, Kienhöfer E, et al. Increasing Post-Digestive Solubility of Curcumin Is the Most Successful Strategy to Improve its Oral Bioavailability: A Randomized Cross-Over Trial in Healthy Adults and In Vitro Bioaccessibility Experiments. Mol Nutr Food Res. 2021 Dec;65(24):e2100613. 

3. Racz LZ, Racz CP, Pop LC, Tomoaia G, et al. Strategies for Improving Bioavailability, Bioactivity, and Physical-Chemical Behavior of Curcumin. Molecules. 2022 Oct 13;27(20):6854

4. Bisht S, Maitra A. Systemic delivery of curcumin: 21st century solutions for an ancient conundrum. Curr Drug Discov Technol. 2009 Sep;6(3):192-9. 

5. Spanoudaki M, Papadopoulou SK, Antasouras G, et al. Curcumin as a Multifunctional Spice Ingredient against Mental Disorders in Humans: Current Clinical Studies and Bioavailability Concerns. Life (Basel). 2024 Apr 5;14(4):479. 

6. Nakagawa Y, Mori K, Yamada S, Mukai S, Hirose A, Nakamura R. The Oral Administration of Highly-Bioavailable Curcumin for One Year Has Clinical and Chondro-Protective Effects: A Randomized, Double-Blinded, Placebo-Controlled Prospective Study. Arthrosc Sports Med Rehabil. 2022 Jan 13;4(2):e393-e402.

7. Nakagawa Y, Mukai S, Yamada S, et al. Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study. J Orthop Sci. 2014 Nov;19(6):933-9.

8. Small GW, Siddarth P, Li Z, et al. Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial. Am J Geriatr Psychiatry. 2018;26(3):266-277.

9 . Sugimoto K, Ikeya K, Bamba S, et al. Highly Bioavailable Curcumin Derivative Ameliorates Crohn's Disease Symptoms: A Randomized, Double-Blind, Multicenter Study. J Crohns Colitis. 2020 Dec 2;14(12):1693-1701. 

10. Kanai M, Otsuka Y, Otsuka K, et al. A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients. Cancer Chemother Pharmacol. 2013 Jun;71(6):1521-30.

11. Hirose A, Kuwabara Y, Kanai Y, et al. Comparative pharmacokinetics of new curcumin preparations and evidence for increased bioavailability in healthy adult participants. Int J Clin Pharmacol Ther. 2022 Dec;60(12):530-538.

12. Kuwabara Y, Hirose A, Lee H, et al. Effects of Highly Bioavailable Curcumin Supplementation on Common Cold Symptoms and Immune and Inflammatory Functions in Healthy Japanese Subjects: A Randomized Controlled Study. J Diet Suppl. 2024;21(1):71-98.

13. Yoshitaka K, Lee H, Hirose A, et al. Improvement in autonomic balance through 12-week supplementation of a novel curcumin formulation in healthy Japanese adults: A randomized, placebo-controlled study. Functional Foods Health Disease Functional Foods in Health and Disease 2024;14(6): 388-406.    .

14. Li X, Kim DY, Sung Y, Kim et al. Effects of 8-week Theracurmin Super (TS-P1; Curcumin) supplementation on exercise-induced oxidative stress: A randomised, double-blind, placebo-controlled parallel clinical trial. Integr Med Res. 2025 Mar;14(1):101099.

15. Kuwabara Y, Lee H, Hirose A, et al. Safety evaluation of high bioavailability curcumin in Healthy Japanese Adults: A Randomized, placebo-controlled, double-blind, parallel-group comparison study. Functional Foods in Health and Disease. 2023;13:. 10.31989/ffhd.v13i12.1207.